Lysergic acid diethylamide, ( buy lsd ) also called lysergide, potent synthetic hallucinogenic drug that can be derived from the ergot alkaloids (as ergotamine and ergonovine, principal constituents of ergot, the grain deformity and toxic infectant of flour caused by the fungus Claviceps purpurea).
LSD is usually prepared by chemical synthesis in a laboratory. Its basic chemical structure is similar to that of the ergot alkaloids, and it is structurally related to several other drugs (e.g., bufotenine, psilocybin, harmine, and ibogaine), which can all block the action of serotonin (the indole amine transmitter of nerve impulses) in brain tissue.
LSD produces marked deviations from normal behaviour, probably the consequence of its ability to inhibit the action of serotonin, though the mechanism of the drug remains uncertain. LSD was used experimentally in medicine as a psychotomimetic agent to induce mental states that were believed to resemble those of actual psychotic diseases (primarily the schizophrenias). After administration, LSD can be absorbed readily from any mucosal surface—even the ear—and acts within 30 to 60 minutes. Its effects usually last for 8 to 10 hours, and occasionally some effects persist for several days. Two serious side effects are the prolongation and transient reappearance of the psychotic reaction.
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